How you’ll spend your day
Teva Branded Pharmaceuticals Products R&D LLC seeks an Associate Scientist in our West Chester, PA office to:
· Troubleshoot or investigate study results, as applicable and independently author technical reports and prepare data presentations for cross-functional teams with minimal supervision.
· Support drafting regulatory filling document (IND, BLA etc).
· Perform routine cell culture experiments including seed culture expansion, bioreactor operation and clarification activities to support early and late -stage process development. This includes, but is not limited to experiments in shaker flasks, Ambr15, Ambr 250, 10L, 50L, 100L and 200L bioreactors, disc-stack centrifuge, and filtration.
· Perform equipment set-up, sterilization, daily operation, sampling and in-process tests (Ex: cell count, viability, gases, metabolites, titer).
· Record experiment results in batch records and electronic lab notebooks in compliance to Good Documentation Practices.
· Perform data analysis as needed.
· Design and conduct experiments to support upstream process development and process characterization activities under managerial supervision.
· Develop experimental plan and execute cell culture and/or harvest studies in laboratory either individually or as a part of working team.
· Maintain and troubleshoot laboratory equipment, coordinate calibration, and manage raw material stocks and supplies in collaboration with relevant internal groups.
· Lead USP projects for timeline driven deliverables in a multi-disciplinary matrix organization.
Approximately 10% domestic travel and 10% international travel required for business purposes including attending conferences and trainings.
Your experience and qualifications
REQUIREMENTS: Master’s degree in Chemical Engineering, Biochemical Engineering, Biotechnology or a related field and 2 years of mammalian cell culture and bioreactor operation experience in a biopharmaceutical company.
Must have experience with:
· Chemical engineering principles;
· Process-scale up and scale-down model qualification activities;
· Early and late-stage cell culture development activities;
· Process characterization activities;
· Design of experiments (DOE) and statistical modeling; and,
· Statistical software for data analysis and statistical modeling including JMP and SIMCA.
· Approximately 10% domestic travel and 10% international travel required for business purposes including attending conferences and trainings.
Please apply at www.tevapharm.com/your-career/ using REQ ID 61694.
